Fully DNA Tested with Ten Clear DNA Health Tests

Both Biscuit and Rolo have an impressive set of clear DNA health tests as detailed below, guaranteeing none of their offspring will be affected by prcd-PRA, rcd4-PRA LOPRA, DM, vWD-1, NE, GM2, FN, HUU, and also providing the reassurance that the sire is DNA clear of MH & MTC-D.

  • DNA tested for Progressive Retinal Atrophy (prcd-PRA) – CLEAR
  • DNA tested for Progressive Retinal Atrophy (rcd4-PRA LOPRA) – CLEAR
  • DNA tested for Degenerative Myelopathy (DM) – CLEAR
  • DNA tested for Von Willebrands Disease Type 1 (vWD-1) – CLEAR
  • DNA tested for Neonatal Encephalopathy (NE) – CLEAR
  • DNA tested for Gangliosidosis / Sandhoff (GM2) – CLEAR
  • DNA tested for Familial Nephropathy (FN) – CLEAR
  • DNA tested for Hyperuricosuria / Urate Stones (HUU) – CLEAR
  • DNA tested for Malignant Hyperthermia (MH) – CLEAR
  • DNA tested for Macrothrombocytopenia (MTC-D) – CLEAR

Our gorgeous stud dogs are extremely well DNA health tested for many conditions which are important to Miniature Poodles and popular mix breeds, including Cockapoos, Labradoodles, Goldendoodles, Poochons, Cavapoos, Cavapoochon, Bordoodle/Colliedoodle, Sproodles, of all generations and mixes. The DNA test results will never change as our boys are genetically clear for life of these conditions and disorders.

All of these health tests are highly important as they guarantee offspring and future generations will be healthy and are the only way to prove that a dog is not a carrier or even worse affected by these conditions when planning your litter. Therefore, our stud dogs are tested clear for all health tests available to Miniature Poodle and Poodle mix offspring and is why we promote DNA health testing for our studs as the health of your girls’ puppies are the most important thing to us.

Our studs’ DNA heath testing explained in full.

Progressive Retinal Atrophy (prcd-PRA)

PRA (Progressive Retinal Atrophy) is an inherited disease that is relevant to many dog breeds and comes in different forms. The prcd (Progressive Rod Cone Degeneration) form of PRA causes the cells in the retina to slowly deteriorate and overtime the affected dog could potentially suffer from night blindness to complete blindness, however some affected dogs may show mild signs of sight lose. The age which a dog shows symptoms of this disease can vary but usually a young adult dog may show symptoms that will overtime deteriorate.

Breeds affected by this condition which may be relevant when breeding with Miniature Poodle studs include American Cocker Spaniel, English Cocker Spaniel, English Cockapoo, American Cockapoo, Golden Retriever, Goldendoodle, Labrador Retriever, Miniature Poodle, Toy Poodle, Standard Poodle, Spanish Water Dog and Labradoodle.

Rolo and Biscuit are DNA tested clear of prcd-PRA to ensure none of their offspring will be affected by this terrible condition. Prcd-PRA is relevant to the Miniature Poodle breed and many other breeds as stated above including many cross breeds such as Cockapoos, Goldendoodles and Labradoodles. A clear DNA result ensures that Rolo and Biscuit are genetically clear and will never be a carrier or affected by this disease.

Progressive Retinal Atrophy (rcd4-PRA LOPRA)

PRA (Progressive Retinal Atrophy) is an inherited disease that is relevant to many dog breeds and comes in different forms. The Rod Cone Dysplasia Type 4 rcd4 LOPRA form is also known as Late Onset PRA as this form may not typically result in vision loss until the dog is in its senior year 7-12 years of age, however the age of onset varies.

Breeds affected by this condition which may be relevant when breeding with Miniature Poodle studs include Miniature Poodle, Poodle, Toy Poodle, Standard Poodle.

Rolo and Biscuit are DNA tested clear of rcd4-PRA LOPRA to ensure none of their offspring will be affected by this terrible form of the condition. rcd4-PRA LOPRA is relevant to the Miniature Poodle breed and many other breeds as stated. A clear DNA result ensures that Rolo and Biscuit are genetically clear and will never be a carrier or affected by this disease.

Degenerative Myelopathy (DM)

Degenerative Myelopathy which is also known as Degenerative Radiculomyelopathy is a progressive disease of the spinal cord. The disease typically affects dogs at a later age between 7 to 14 years old. It tends to start with loss of coordination in the hind limbs, muscle weakness, difficultly walking, balance problems and may lead to a leg being dragged or the dog becoming crippled as the disease progresses, which may happen over a few months to a few years.

Breeds affected by this condition which may be relevant when breeding with Miniature Poodle studs include All Dog Breeds including Cavalier King Charles Spaniel, Cavapoo, Cocker Spaniel, Cockapoo, Golden Retriever, Goldendoodle, Labrador Retriever, Labradoodle, and Poodle.

DM is relevant all dog breeds including the Poodle, Labrador, Golden Retriever and Cocker Spaniel breeds therefore Rolo and Biscuit have been DNA tested with a clear result to avoid any of their poodle or poodle mix offspring being affected by this terrible condition. It is also important to consider that first cross and further generation mix breed litters should also benefit from this testing, if Rolo or Biscuit mated with a further generation Miniature Labradoodle (F1, F2 etc), Cockapoo (F1, F2 etc) or Miniature Goldendoodle (F1, F2 etc) that happened to be a carrier of this disease and our studs were not clear but were also a carrier or affected then the outcome of the litter could potentially produce a percentage of affected puppies.

Von Willebrands Disease Type 1 (vWD-1)

Von Willebrand disease (vWD) is an inherited bleeding disorder in dogs which is caused by lack of von Willebrand factor which is a protein that helps with the blood clotting process. If a dog is affected from vWD the blood may not clot well and causes prolonged bleeding. The disorder can range from mild prolonged bleeding to life threatening haemorrhages in some cases.

Breeds affected by this condition which may be relevant when breeding with Miniature Poodle studs include American Cockapoo, English Cockapoo, Miniature Poodle, Toy Poodle, Standard Poodle, and Labradoodle.

vWD-1 is relevant to the Miniature Poodle breed therefore Rolo and Biscuit have been DNA tested clear for this condition to avoid any of their poodle offspring being affected by this terrible condition. It is also important to consider that any further generation mix breed litters should also benefit from this testing as if Rolo or Biscuit were mated with a further generation cockapoo (F1, F1b, F2) or labradoodle (F1, F1b, F2) that happened to be a carrier of this disease and our studs were not clear but were also a carrier or affected the outcome of the litter could potentially produce a percentage of affected puppies.

Neonatal Encephalopathy (NE)

Neonatal Encephalopathy with seizures is sometimes referred to as NE or NEWS which is a developmental brain disease relevant to the Standard Poodle breed and can affect young puppies. Affected puppies show extreme weakness, can have body tremors and seizures and do not survive to 7/8 weeks of age.

Breed affected is Standard Poodle.

Rolo and Biscuit are DNA tested clear for Neonatal Encephalopathy (NE) which is actually a genetic brain disease relevant to the Standard Poodle breed. Miniature Poodles do not carry NE; however, this DNA test simply provides valid confirmation that our studs are genetically clear of NE when breeding any mix breed especially any Standard Poodle cross breeds as NE is relevant to the Poodle family.

Gangliosidosis Sandhoff (GM2)

Gangliosidosis is also known as GM2 or Sandhoff Disease and is a progressive neurodegenerative Lysosomal Storage disease. Dogs affected are unable to break down certain enzymes and causes a progressive destruction of the central nervous system. Symptoms may include loss of vision, walking difficulties, loss of balance, head tremors and vomiting. Dogs affected by GM2 may start to show symptoms of this neurologic disease at around the age of 9 to 12 months. This disease can progress at differing rates, but it is ultimately fatal.

Breed affected is Toy Poodle.

Rolo and Biscuit are DNA tested clear for Gangliosidosis Sandhoff GM2 which is actually a genetic neurological disease relevant to the Toy Poodle. Miniature Poodles do not carry GM2, however this DNA test simply provides valid confirmation that our studs are genetically clear of GM2 when breeding any mix breed especially any Toy Poodle cross breeds as GM2 is relevant to the Poodle family.

Familial Nephropathy (FN)

Familial Nephropathy is a fatal kidney disease which can affect English Cocker Spaniels at a young age between 6 months and 2 years. This disease can progress at differing rates and also have differing symptom, but it is ultimately fatal.

Breed affected is English Cocker Spaniel.

Rolo and Biscuit are DNA tested clear for Familial Nephropathy (FN) which is actually a genetic kidney disease relevant to the English Cocker Spaniel breed. Miniature Poodles do not carry FN, however this DNA test simply provides valid confirmation that our studs are genetically clear of FN when breeding any generation of Cockapoos which is reassuring to know by having a certificate to prove this and confirms Rolo and Biscuit’s suitability as sires, especially if an English Cocker Spaniel or English Cockapoo may be a carrier of this disease.

Hyperuricosuria / Urate Stones (HUU)

Hyperuricosuria is also known as Urate Stones which is the elevated levels of uric acid in the urine. Dogs affected from this condition are prone to form stones in their bladders or sometimes their kidneys.

Breeds affected includes All Dog Breeds.

HUU is relevant to all dog breeds and mix breeds therefore Rolo and Biscuit have been DNA tested with clear results to avoid any of their poodle or poodle mix offspring being affected by this terrible condition. It is also important to consider that any further generation mix breed litters should also benefit from this testing as if Rolo or Biscuit were mated with any pure breed such as a Miniature Poodle, Cocker Spaniel or Labrador or any mix breed such as a Cockapoo, Labradoodle, Goldendoodle, Cavapoo, Cavapoochon etc that happened to be a carrier of this disease and our studs were not clear but were also a carrier or affected the outcome of the litter could potentially produce a percentage of affected puppies.

Malignant Hyperthermia (MH)

Malignant Hyperthermia which is also known as MH and sometimes referred to as canine stress syndrome. It’s triggered by exposure to anaesthetic agents including succinylcholine or volatile. It’s an inherited disorder of skeletal muscle characterized by hypercarbia, rhabdomyolysis, generalized skeletal muscle contracture, cardiac dysrhythmia, and renal failure. Possible symptoms can include muscle stiffness, rapid breathing, high temperature, seizures and dilated pupils. However specific interventions, including use of the calcium release channel antagonist dantrolene, are efficacious in reversing signs of this canine syndrome.

Breeds affected includes All Dog Breeds.

MH is relevant to all dog breeds and mix breeds therefore Rolo and Biscuit have been DNA tested with clear results. It is a dominant gene therefore both parents need to be clear to produce clear or unaffected offspring, however this DNA test provides valid confirmation that our studs are genetically clear of MH when breeding with any breed which is reassuring to know by having a certificate to prove this.

Macrothrombocytopenia (MTC-D)

Macrothrombocytopenia which is also referred to as MTC-D is an inherited blood disorder characterised by oversized platelets and a low platelet count. The name is derived from the words macro (large) and thrombocyte (platelets), cells that assist in the blood clotting function. It is important to note that these dogs may mistakenly be considered to have an underlying disease that results in thrombocytopenia, such as immune-mediated thrombocytopenia, tick-borne infection or a bone marrow disorder.

Breeds affected by this condition which may be relevant when breeding with Miniature Poodle studs include Labrador Retriever, Miniature Poodle, Toy Poodle, Standard Poodle, Cocker Spaniel, Cavalier King Charles Spaniel and Bishon Frise.

MTC-D is relevant to Miniature Poodles and many other breeds therefore Rolo and Biscuit have been DNA tested with clear results. It is a dominant gene therefore both parents need to be clear to produce clear or unaffected offspring, however this DNA test provides valid confirmation that our studs are genetically clear of MTC-D when breeding with any breed which is reassuring to know by having a certificate to prove this.